Clinical Proof
The induction of human superoxide dismutase and catalase in vivo: A fundamentally new approach to antioxidant therapy, Free Radical Biology and Medicine (2006)
The results of a peer-reviewed study (Free Radical Biology and Medicine, 2006) showed Protandim eliminates the age-related increase in cell aging factors.
In the clinical trials, blood samples from men and women, young and old, consistently demonstrated that after 30 days, taking one caplet a day, test subjects realized a 40 percent average decrease in TBARS—the progressive aging rate of a 20 year old.
When maintained for 120 days, Protandim significantly increased activity of SOD and CAT antioxidant enzymes by 54 percent, substantially increasing the body’s antioxidant defenses.*
Click here to view the study.

Normal subjects before supplementation with Protandim showed an age-dependent increase in TBARS (blue circles). The levels of TBARS dropped an average of 40% (p<0.0001) after 30 days of Protandim supplementation (green circles), and the age-related increase in TBARS virtually disappeared. This effect (gray circles) was maintained at 120 days with continued Protandim use.
Prestigious American Heart Association Journal, Circulation, Publishes New Peer-Reviewed Study Involving Protandim®
Dr. Norbert Voelkel and researchers at Virginia Commonwealth University (VCU), demonstrated the ability of Protandim, the Company’s patented dietary supplement composed of five highly synergistic “indirect antioxidants”, to protect the heart in a laboratory model of pulmonary hypertension in rats. “We are encouraged by the results of this study, which was independently funded and independently conducted by Dr. Voelkel and his colleagues at VCU,” stated David Brown, President & CEO of LifeVantage.
“These results illustrate the unique antioxidant, anti-inflammatory, and anti-fibrotic properties of Protandim. Scientists have long known of the involvement of oxidative stress in disease processes, and this study is a significant example of how oxidative stress affects susceptibility to right heart failure in animals. Although it would be premature to conclude that similar benefits would be seen in humans, these remarkable results open the door to the possibility of future research on pulmonary hypertension and Protandim in humans.”
Click here to view the press
release.
Synergistic induction of heme oxygenase-1 by the components of an antioxidant supplement Protandim, Free Radical Biology and Medicine (2008)
Results of a new peer-reviewed study (Free Radical Biology & Medicine, on November 18, 2008) clearly demonstrate that Protandim produces a 300 percent increase in glutathione, which is a key antioxidant and anti-aging factor. In addition, the study shows that Protandim’s synergistic formulation provides more antioxidant power than any food or conventional supplement.
Click here to view the study.
2009 Peer Reviewed Study from Louisiana State, PLoS ONE Journal.
Peer Reviewed Study from Louisiana State University, "Protandim®, a Fundamentally New Antioxidant Approach in Chemoprevention Using Mouse Two-Stage Skin Carcinogenesis as a Model," Published in PLoS ONE Journal.
Click here to view the study.
PROTANDIM HAS BEEN ISSUED THREE PATENTS AND HAS BEEN FEATURED ON ABC's PRIMETIME.
2006 Clinical Protandim Study (pdf)
2008 Clinical Protandim Study (pdf)
2009 Louisiana State Peer Reviewed Study
2009 Independent VCU Heart Study
press release (pdf)
Protandim has been studied by numerous universities in their own funded trials because scientists who know about the true science of oxidative stress are so excited about the potential. These universities include:
University of Colorado
Denver Health Medical Center
Children's Hospital, Denver
Virginia Commonwealth University
Colorado State University
University of Florida
University of Kentucky
University of Michigan
Louisiana State University
Ohio State University
Vanderbilt University
Glamorgan University, Wales
Sahlgrenska University Hospital, Goteborg, Sweden
University Hospital, Brno, Czech Republic
Mexican Institute of Social Security, Mexico City